Vitamin D and Its Role in Modulating Immune System: A Narrative Literature Review
نویسندگان
چکیده
Vitamin D is recognized for its pivotal role in maintaining calcium-phosphorus homeostasis and regulating bone metabolism. The beneficial effects of vitamin on the protective function immune system are seen innate system. It increases production defensin β2 cathelicidin by macrophages, monocytes, keratinocytes response to infection. Cathelicidin produced neutrophils, cells lining epithelial surfaces such as skin, respiratory, digestive tracts. Recent research showed that exerts potent immunomodulatory modulating adaptive systems. This led recognition various disease conditions associated with deficiency. narrative review aimed describe molecular mechanisms effect.
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ژورنال
عنوان ژورنال: Open Access Indonesian Journal of Medical Reviews
سال: 2023
ISSN: ['2807-6257']
DOI: https://doi.org/10.37275/oaijmr.v3i1.282